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Global Bispecific Antibodies Market to reach USD 105.94 billion by the end of 2030.

Global Bispecific Antibodies Market Size Study & Forecast, by Indication (Cancer, Inflammatory & Autoimmune Disorders, Others), and Regional Analysis, 2023-2030

Product Code: HLSB-13490438
Publish Date: 4-10-2023
Page: 200

Global Bispecific Antibodies Market is valued at approximately USD 5.73 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 44.0% over the forecast period 2023-2030. Bispecific antibodies are a class of therapeutic proteins created to attach to two distinct target molecules simultaneously. These antibodies have two separate antigen-binding sites that recognize a different antigen or receptor because of genetic engineering. Bispecific antibodies assemble these molecules, control their interactions, or transport medicinal substances to body parts by attaching two distinct targets. Bispecific antibodies provide several benefits compared to conventional monoclonal antibodies, which normally bind to a single target. They are used to target numerous disease-related pathways concurrently or to divert immune cells away from healthy tissue and toward tumor cells. The growing demand for targeted and personalized therapies, significant advancements in antibody engineering technologies, along with increasing collaborations and partnerships between local and international stakeholders are the key factors that are propelling the market demand during the estimated period.

In addition, the surge in the incidences of cancer cases is fueling the demand for a range of treatment alternatives including biospecific antibodies particularly those designed as immune checkpoint inhibitors or T cell engagers, which, in turn, accelerating the market growth across the world. According to The Global Cancer Observatory (GCO), in 2020, about 19.3 million new cases of cancer were reported worldwide and this number is expected to increase to 30.2 million in the year 2040. Biospecific antibodies redirect immune cells to attack tumor cells, leading to tumor regression and improved patient outcomes. Moreover, the increasing investment in biologics research and development, as well as the robust growth of the biopharmaceutical pipeline present various lucrative opportunities over the forecast years. However, the complex development and manufacturing and regulatory challenges are challenging the market growth throughout the forecast period of 2023-2030.

The key regions considered for the Global Bispecific Antibodies Market study include Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 owing to the increasing approval for several bispecific antibodies by regulatory bodies, growing investment in R&D activities, along with the presence of several leading market players. For instance, in October 2022, the first bispecific B-cell maturation antigen, teclistamab-cqyv (Tecvayli, Janssen Biotech, Inc.), received FDA approval. In addition, companies are increasingly participating in partnerships and collaborations to use complementary scientific expertise and technology to create bispecific antibodies. These partnerships promoted research and development initiatives, which has further accelerated market expansion. Europe is expected to grow at a substantial CAGR over the forecast years. The surging demand for bispecific antibodies, rising focus on technological advancements, as well as increasing collaborations and partnerships between local and international stakeholders are significantly propelling the market demand across the region.

Major market players included in this report are:
Amgen, Inc.
Bayer AG
Dow Pharmaceutical Solutions
ImmunGene, Inc.
Immunocore Limited
Merck & Co., Inc.
Novartis AG
Pfizer, Inc.
F. Hoffmann-La Roche AG
Akeso, Inc.

Recent Developments in the Market:
Ø In January 2023, Genentech, Inc., an American biotechnology corporation announced that the company has received FDA approval for the company’s bispecific antibody that is specially designed for lymphoma. This approval enables the company to market their bispecific antibody across the region.
Ø In May 2023, Genmab A/S unveiled that the U.S. Food and Drug Administration (FDA) has approved EPKINL (epcoritamab-bysp) as the first and only T-cell engaging bispecific antibody for the treatment of adult patients with diffuse large B-cell lymphoma (DLBCL), not otherwise specified (NOS), including DLBCL arising from indolent lymphoma, and high-grade B-cell lymphoma, following two or more lines of systemic therapy.

Global Bispecific Antibodies Market Report Scope:
ü Historical Data – 2020 – 2021
ü Base Year for Estimation – 2022
ü Forecast period – 2023-2030
ü Report Coverage – Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
ü Segments Covered – Indication, Region
ü Regional Scope – North America; Europe; Asia Pacific; Latin America; Middle East & Africa
ü Customization Scope – Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Indication:
Cancer
Inflammatory & Autoimmune Disorders
Others

By Region:

North America
U.S.
Canada

Europe
UK
Germany
France
Spain
Italy
ROE

Asia Pacific
China
India
Japan
Australia
South Korea
RoAPAC

Latin America
Brazil
Mexico

Middle East & Africa
Saudi Arabia
South Africa
Rest of Middle East & Africa

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Billion)
1.2.1. Bispecific Antibodies Market, by Region, 2020-2030 (USD Billion)
1.2.2. Bispecific Antibodies Market, by Indication, 2020-2030 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global Bispecific Antibodies Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Industry Evolution
2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global Bispecific Antibodies Market Dynamics
3.1. Bispecific Antibodies Market Impact Analysis (2020-2030)
3.1.1. Market Drivers
3.1.1.1. Increasing demand for targeted and personalized therapies
3.1.1.2. Surge in the incidences of cancer cases
3.1.2. Market Challenges
3.1.2.1. Complex development and manufacturing
3.1.2.2. Regulatory challenges
3.1.3. Market Opportunities
3.1.3.1. Increasing investment in biologics research and development
3.1.3.2. Robust growth of the biopharmaceutical pipeline
Chapter 4. Global Bispecific Antibodies Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion
Chapter 5. Global Bispecific Antibodies Market, by Indication
5.1. Market Snapshot
5.2. Global Bispecific Antibodies Market by Indication, Performance – Potential Analysis
5.3. Global Bispecific Antibodies Market Estimates & Forecasts by Indication 2020-2030 (USD Billion)
5.4. Bispecific Antibodies Market, Sub Segment Analysis
5.4.1. Cancer
5.4.2. Inflammatory & Autoimmune Disorders
5.4.3. Others
Chapter 6. Global Bispecific Antibodies Market, Regional Analysis
6.1. Top Leading Countries
6.2. Top Emerging Countries
6.3. Bispecific Antibodies Market, Regional Market Snapshot
6.4. North America Bispecific Antibodies Market
6.4.1. U.S. Bispecific Antibodies Market
6.4.1.1. Indication breakdown estimates & forecasts, 2020-2030
6.4.2. Canada Bispecific Antibodies Market
6.5. Europe Bispecific Antibodies Market Snapshot
6.5.1. U.K. Bispecific Antibodies Market
6.5.2. Germany Bispecific Antibodies Market
6.5.3. France Bispecific Antibodies Market
6.5.4. Spain Bispecific Antibodies Market
6.5.5. Italy Bispecific Antibodies Market
6.5.6. Rest of Europe Bispecific Antibodies Market
6.6. Asia-Pacific Bispecific Antibodies Market Snapshot
6.6.1. China Bispecific Antibodies Market
6.6.2. India Bispecific Antibodies Market
6.6.3. Japan Bispecific Antibodies Market
6.6.4. Australia Bispecific Antibodies Market
6.6.5. South Korea Bispecific Antibodies Market
6.6.6. Rest of Asia Pacific Bispecific Antibodies Market
6.7. Latin America Bispecific Antibodies Market Snapshot
6.7.1. Brazil Bispecific Antibodies Market
6.7.2. Mexico Bispecific Antibodies Market
6.8. Middle East & Africa Bispecific Antibodies Market
6.8.1. Saudi Arabia Bispecific Antibodies Market
6.8.2. South Africa Bispecific Antibodies Market
6.8.3. Rest of Middle East & Africa Bispecific Antibodies Market

Chapter 7. Competitive Intelligence
7.1. Key Company SWOT Analysis
7.1.1. Company 1
7.1.2. Company 2
7.1.3. Company 3
7.2. Top Market Strategies
7.3. Company Profiles
7.3.1. Amgen, Inc.
7.3.1.1. Key Information
7.3.1.2. Overview
7.3.1.3. Financial (Subject to Data Availability)
7.3.1.4. Product Summary
7.3.1.5. Recent Developments
7.3.2. Bayer AG
7.3.3. Dow Pharmaceutical Solutions
7.3.4. ImmunGene, Inc.
7.3.5. Immunocore Limited
7.3.6. Merck & Co., Inc.
7.3.7. Novartis AG
7.3.8. Pfizer, Inc.
7.3.9. F. Hoffmann-La Roche AG
7.3.10. Akeso, Inc.
Chapter 8. Research Process
8.1. Research Process
8.1.1. Data Mining
8.1.2. Analysis
8.1.3. Market Estimation
8.1.4. Validation
8.1.5. Publishing
8.2. Research Attributes
8.3. Research Assumption

At Bizwit Research and Consultancy, we employ a thorough and iterative research methodology with the goal of minimizing discrepancies, ensuring the provision of highly accurate estimates and predictions over the forecast period. Our approach involves a combination of bottom-up and top-down strategies to effectively segment and estimate quantitative aspects of the market, utilizing our proprietary data & AI tools. Our Proprietary Tools allow us for the creation of customized models specific to the research objectives. This enables us to develop tailored statistical models and forecasting algorithms to estimate market trends, future growth, or consumer behavior. The customization enhances the accuracy and relevance of the research findings.
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Data Collection:
To determine the appropriate methods of data collection based on the research objectives, we consider both primary and secondary sources. Primary data collection involves gathering information directly from various industry experts in core and related fields, original equipment manufacturers (OEMs), vendors, suppliers, technology developers, alliances, and organizations. These sources encompass all segments of the value chain within the specific industry. Through in-depth interviews, we engage with key industry participants, subject-matter experts, C-level executives of major market players, industry consultants, and other relevant experts. This allows us to obtain and validate critical qualitative and quantitative information while evaluating market prospects. AI and Big Data are instrumental in our primary research, providing us with powerful tools to collect, analyze, and derive insights from data efficiently. These technologies contribute to the advancement of research methodologies, enabling us to make data-driven decisions and uncover valuable findings.
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Our team of experts carefully examine the gathered data using suitable statistical techniques and qualitative analysis methods. For quantitative analysis, we employ descriptive statistics, regression analysis, and other advanced statistical methods, depending on the characteristics of the data. This analysis may also incorporate the utilization of AI tools and big data analysis techniques to extract meaningful insights.
To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
Our proprietary data tools play a crucial role in deriving our market estimates and forecasts. Each study involves the creation of a unique and customized model. The model incorporates the gathered information on market dynamics, technology landscape, application development, and pricing trends. AI techniques, such as machine learning and deep learning, aid us to analyze patterns within the data to identify correlations, trends, and relationships. By recognizing patterns in consumer behavior, purchasing habits, or market dynamics, our AI algorithms aid us in more precise estimations of market size. These factors are simultaneously analyzed within the model, allowing for a comprehensive assessment. To quantify their impact over the forecast period, correlation, regression, and time series analysis are employed.
To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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